Rachel I. Gafni received her BA from Barnard College/Columbia University and her MD from Temple University School of Medicine. She completed pediatric residency at the Children’s Hospital of Philadelphia followed by a pediatric endocrinology fellowship at the National Institutes of Health (NIH), serving as a commissioned officer in the US Public Health Service for 6 years. Following a 5-year appointment at the University of Maryland Medical Center, Dr. Gafni returned to the NIH in 2007 in the National Institute of Dental and Craniofacial Research, becoming a Senior Research Physician in 2018. She is also faculty in the Pediatric Bone Health Program at Children’s National Hospital, an Adjunct Associate Professor at the George Washington School of Medicine, and the program director for the pediatric endocrinology fellowship in the Eunice Kennedy Shriver National Institute of Child Health and Human Development. Dr. Gafni’s primary interests involve the study of conditions affecting calcium and phosphate metabolism, the teeth, and the skeleton, with a focus on developing improved therapies to benefit patients. To that end, she serves as a principal or associate investigator on clinical research protocols evaluating and treating individuals with hypoparathyroidism, autosomal dominant hypocalcemia, osteoporosis, hypophosphatemic rickets, tumor-induced osteomalacia, hyperphosphatemic familial tumoral calcinosis, generalized arterial calcification of infancy, dermatomyositis-related calcinosis, and other bone and mineral disorders.